- African-American Gospel Ensemble -- The Gospel Ensemble provides religious and musical performances for the Canisius community.
- Arts Promotion Club -- This club enriches the cultural environment on campus and aids in programming each concert series, as well as the promotion of each concert series.
- Canisius College Chorale -- The Chorale provides choral activities for the entertainment and enjoyment of its members, Canisius, and the community. Events include annual Christmas and spring concerts and activities. No criteria to become a member; open to students, faculty, staff, and anyone attending an area college.
- Canisius Songwriters Collective -- Canisius has a large and vibrant muscially creative community. The Songwriters Collective nourishes, cultivates, and displays the talents of its members through activities, events, and performances.
- Chamber Music Ensemble -- The ensemble was organized for instrumentalists and/or vocalists interested in rehearsing classical chamber music in small ensembles. Students are assigned to ensembles based on instrumentation and experience. Ensembles are coached by members of the Fine Arts faculty. Optional opportunities to perform in public are offered.
- Chamber Orchestra -- This organization performs a wide range of orchestral literature from the baroque period through the twentieth century. Directed by a professional musician; rehearsals and concerts provide students with experiences in the orchestral arts.
- Concert Band -- The Concert Band is an instrumental organization that performs a wide range of music literature from today and from the past. Directed by a professional musician, rehearsals and concerts provide students with the opportunity to perform at a high level.
- Contemporary Music Ensemble -- The ensemble provides instrumental and vocal music for Sunday masses as well as other special services both on and off campus.
- Dance Griffs -- Dance Griffs is a great opportunity for those interested in dance. Presenting different forms of dancing for the school and community for various events.
- GSquad (Step Team) -- G Squad is an opportunity for those interested in dance. Presenting different forms of dancing for the school and community for various events.
- Jazz Ensemble -- Jazz Ensemble provides an atmosphere for Jazz and Big Band performances to the community and the college campus.
- Little Theatre -- Little Theatre presents different forms of theatre to the Canisius community. Includes acting, stage crew, costuming, make-up, and lighting.
- Pep Band -- The Pep Band performs at various school events and shows support for Canisius College. Pep Band members will have scheduled practices and will perform at various sporting events and school activities.